Obesity-related complications1
A-fib, arterial fibrillation; CAD, coronary artery disease; CHF, congestive heartfailure; ED, erectile dysfuntion; EOM, eosinophilic otitis media; GDM, gestational diabetes mellitus; GORD, gastro-oesophageal reflex disease; HCC, hepatocellular carcinoma; HLD, hyperlipidaemia; HTN, hypertension; MM, multiple myeloma; NAFLD, nonalcoholic fatty liver disease; OA, osteoarthritis; VTE, venous thromboembolism.
The complications associated with obesity can have far-reaching, wide-ranging impacts,2 and can significantly shorten people's lives.3
People with obesity may experience:
The benefits of medical intervention
There are significant clinical benefits to medical obesity intervention.8 Effective weight management is associated with improvements in both physical and psychological well-being.8-9
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Learn more about ORCs throughout the body
CVD and HFpEF
MASH
Diabetes
Women's health
HFpEF, heart failure with preserved ejection fraction; MASH, metabolic dysfunction-ossaciated steatohepatitis.
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References
- Yuen MM, Earle RL, Kadambi N, et al. T-P-3166: a systematic review and evaluation of current evidence reveals 236 obesity-associated disorders (ObAD). Poster abstract presentation at: Obesity Society Annual Meeting at ObesityWeek 2016; October 31–November 4, 2016; New Orleans, LA.
- Rozjabek H, Fastenau J, LaPrade A, Sternbach N. Adult obesity and health-related quality of life, patient activation, work productivity, and weight loss behaviors in the United States. Diabetes Metab Syndr Obes. 2020;13:2049–2055.
- Grover SA, Kaouache M, Rempel P, et al. Years of life lost and healthy life-years lost from diabetes and cardiovascular disease in overweight and obese people: a modelling study. Lancet Diabetes Endocrinol. 2015;3(2):114–122.
- GBD 2015 Obesity Collaborators; Afshin A, Forouzanfar MH, et al. Health effects of overweight and obesity in 195 countries over 25 years. N Engl J Med. 2017;377(1):13–27.
- Khafagy R, Dash S. Obesity and cardiovascular disease: the emerging role of inflammation. Front Cardiovasc Med. 2021;8:768119.
- Sarwer DB, Polonsky HM. The psychosocial burden of obesity. Endocrinol Metab North Am. 2016;45(3):677–688.
- Rubino F, Puhl RM, Cummings DE, et al. Joint international consensus statement for ending stigma of obesity. Nat Med. 2020;26:485–497.
- Horn D, Almandroz JP, Look M. What is clinically relevant weight loss for your patients and how can it be achieved? Postgrad Med. 2022;134(4):359–375.
- Jensen MD, Ryan DH, Apovian CM, et al. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society [published correction appears in Circulation. 2014 Jun 24;129(25 Suppl 2):S139–S140]. Circulation. 2014;129(25 Suppl 2):S102–S138.
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